ABSTRACT
Hansen solubility parameters (HSP) can be used to gain insight into many safety and environmental issues. These include substitution to more desirable materials, products, and processes, where a listing of solvents having HSP similarity to the one(s) to be substituted provides an overview of the potential choices for improvement. Selection of suitable chemical protective clothing can be improved by considering HSP correlations of breakthrough time. Evaluating risks for inadvertent chemical uptake in plastic can be helped by HSP correlations of chemical resistance and/or permeation phenomena. Similarity of HSP suggests which chemicals are most likely to be rapidly absorbed into given plastic types. These same approaches can be used to evaluate the potential for uptake of chemicals through human skin.
