ABSTRACT

Transport of fluid and metabolites from blood to tissue is critically important for maintaining the viability and function of cells within the body. Similarly, transport of fluid and waste products from tissue to the lymphatic system of vessels and nodes is also crucial to maintain tissue and organ health. Therefore, it is important to understand the mechanisms for transporting fluid containing micro-and macromolecules from blood to tissue and the drainage of this fluid into the lymphatic system. Because of the succinct nature of this chapter, readers are encouraged to consult more complete reviews of blood/tissue/lymphatic transport by Aukland and Reed [1993], Bert and Pearce [1984], Casley-Smith [1982], Curry [1984], Hargens [1986], Jain [1987], Lai-Fook [1986], Levick [1984], Reddy [1986], Schmid-Scho¨nbein [1990], Schmid-Scho¨nbein and Zweifach [1994], Staub [1988], Staub et al. [1987], Taylor and Granger [1984], Wei et al. [2003], Zweifach and Lipowsky [1984], and Zweifach and Silverberg [1985].