ABSTRACT
CASRN: 53-96-3; DOT: 3143; molecular formula: C15H13NO; FW: 223.27; RTECS: AB9450000; Merck Index: 12, 4192 Physical state and color: Tan crystalline solid or needles Melting point (°C): 194 (Weast, 1986) Diffusivity in water (x 10-5 cm2/sec): 0.52 at 20 °C using method of Hayduk and Laudie (1974) Soil organic carbon/water partition coefficient, log Koc: 3.20 (calculated, Mercer et al., 1990) Octanol/water partition coefficient, log Kow: 3.28 (quoted, Mercer et al., 1990) Solubility in organics: Soluble in acetone, acetic acid, alcohol (Weast, 1986), glycols, and fat solvents (Windholz et al., 1983) Solubility in water: 10.13 mg/L at 26.3 °C (Ellington et al., 1987) Environmental fate: Biological. In the presence of suspended natural populations from unpolluted aquatic systems, the second-order microbial transformation rate constant determined in the laboratory was reported to be 4.8 ± 2.8 x 10-12 L/organism⋅h (Steen, 1991). Chemical/Physical. Based on first-order rate constants determined at 85.5 °C, hydrolysis halflives at pH values of 2.49, 2.97, 7.34, 9.80, 10.25, and 10.39 were 4.2, 12, 41, 13, 7.2, and 1.9 d, respectively (Ellington et al., 1987). Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987). At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities were 318, 240, 180, and 140 mg/g, respectively (Dobbs and Cohen, 1980). Exposure limits: Potential occupational carcinogen. Given that no standards have been established, NIOSH (1997) recommends the most reliable and protective respirators be used, i.e., a self-contained breathing apparatus that has a full facepiece and is operated under positive-pressure or a supplied-air respirator that has a full facepiece and is operated under pressure-demand or under positive-pressure in combination with a self-contained breathing apparatus operated under
OSHA recommends that worker exposure to this chemical is to be controlled by use of engineering control, proper work practices, and proper selection of personal protective equipment. Specific details of these requirements can be found in CFR 1910.1003-1910.1016. Toxicity: Acute oral LD50 for mice 1,020 mg/kg (quoted, RTECS, 1985). Uses: Preparation of derivatives for biochemical and cancer research, i.e., studying carcinogenicity and mutagenicity of aromatic amines.
