ABSTRACT
CASRN: 541-85-5; DOT: 2271; DOT label: Combustible liquid; molecular formula: C8H16O; FW: 128.21; RTECS: MJ7350000; Merck Index: 12, 3810 Physical state, color, and odor: Colorless liquid with a fruity odor Melting point (°C): -57.1 (NIOSH, 1997) Boiling point (°C): 158.5 (NIOSH, 1987) Density (g/cm3): 0.820-0.824 at 20/20 °C (Windholz et al., 1983) 0.85 at 0 °C (quoted, Verschueren, 1983) Diffusivity in water (x 10-5 cm2/sec): 0.68 at 20 °C using method of Hayduk and Laudie (1974) Flash point (°C): 43 (Acros Organics, 2002) 59 (NIOSH, 1997) Henry’s law constant (x 10-4 atm⋅m3/mol): 1.30 at 20 °C (approximate - calculated from water solubility and vapor pressure) Soil organic carbon/water partition coefficient, log Koc: Unavailable because experimental methods for estimation of this parameter for aliphatic hydrocarbons are lacking in the documented literature Octanol/water partition coefficient, log Kow: 1.96 using method of Hansch et al. (1968) Solubility in organics: Mixes readily with alcohols, ether, ketones, and other organic solvents (Patnaik, 1992) Solubility in water (wt %): 0.275 at 0 °C, 0.227 at 9.3 °C, 0.192 at 19.9 °C, 0.151 at 30.9 °C, 0.151 at 40.8 °C, 0.142 at 50.2 °C, 0.124 at 59.8 °C, 0.132 at 70.5 °C, 0.128 at 80.2 °C, 0.131 at 90.5 °C (shake flask-GC, Stephenson, 1992) Vapor density: 5.24 g/L at 25 °C, 4.43 (air = 1)
2 at 20 °C (NIOSH, 1987) 2 at 25 °C (quoted, Verschueren, 1983) Environmental fate: Chemical/Physical. 5-Methyl-3-heptanone will not hydrolyze because it does not contain a hydrolyzable functional group. Exposure limits: NIOSH REL: TWA 25 ppm (130 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 25 ppm. Symptoms of exposure: May irritate eyes, nose, and throat. At high concentrations, ataxia, prostration, respiratory, pain and narcosis may occur (Patnaik, 1992). Toxicity: Acute oral LD50 for guinea pigs 2,500 mg/kg, mice 3,800 mg/kg, rats 3,500 mg/kg (quoted, RTECS, 1985). Uses: Solvent for vinyl resins, nitrocellulose-alkyd and nitrocellulose-maleic acid resins.
