ABSTRACT
CASRN: 79-46-9; DOT: 2608; DOT label: Combustible liquid; molecular formula: C3H7NO2; FW: 89.09; RTECS: TZ5250000; Merck Index: 12, 6725 Physical state, color, and odor: Colorless, oily liquid with a mild, fruity odor. 2-Nitropropane was detected in two studies at concentrations of 3.1 and 5.2 ppmv (Crawford et al., 1984). Melting point (°C): -93 (Weast, 1986) Boiling point (°C): 120 (Weast, 1986) Density (g/cm3): 0.9876 at 20 °C (Weast, 1986) 0.9821 at 25 °C (Windholz et al., 1983) Diffusivity in water (x 10-5 cm2/sec): 0.94 at 20 °C using method of Hayduk and Laudie (1974) Dissociation constant, pKa: 7.675 at 25 °C (Dean, 1987) Flash point (°C): 24.1 (NIOSH, 1997) Lower explosive limit (%): 2.6 (NIOSH, 1997) Upper explosive limit (%): 11.0 (NIOSH, 1997) Henry’s law constant (x 10-5 atm⋅m3/mol): 8.92 at 20.00 °C, 15.3 at 30.00 °C, 24.4 at 40.00 °C, 36.9 at 50.00 °C (inert gas stripping, Beneš
and Dohnal, 1999) Ionization potential (eV): 10.74 (Lias, 1998) Bioconcentration factor, log BCF: 1.85 (activated sludge), 1.30 (algae) (Freitag et al., 1985) Soil organic carbon/water partition coefficient, log Koc: Unavailable because experimental methods for estimation of this parameter for nitroaliphatics are
adsorption to soil will be low (Lyman et al., 1982). Octanol/water partition coefficient, log Kow: Unavailable because experimental methods for estimation of this parameter for nitroaliphatics are lacking in the documented literature Solubility in organics: Miscible with many organic solvents (Windholz et al., 1983) Solubility in water (wt %): 3.07 at 0 °C, 1.80 at 19.7 °C, 1.70 at 30.9 °C, 1.78 at 40.0 °C, 1.79 at 50.5 °C, 2.07 at 61.1 °C,
2.09 at 70.6 °C, 2.26 at 81.0 °C, 2.36 at 90.2 °C (shake flask-GC, Stephenson, 1992) As mole fraction: 4.37 x 10-3 at 20 °C (shake flask-RPLC, Hafkenscheid and Tomlinson, 1981) Vapor density: 3.64 g/L at 25 °C, 3.08 (air = 1) Vapor pressure (mmHg): 13 at 20 °C (NIOSH, 1997) Environmental fate: Photolytic. Anticipated products from the reaction of 2-nitropropane with ozone or OH radicals in the atmosphere are formaldehyde and acetaldehyde (Cupitt, 1980). Exposure limits: Potential occupational carcinogen. NIOSH REL: IDLH 100 ppm; OSHA PEL: TWA 25 ppm (90 mg/m3); ACGIH TLV: TWA 10 ppm (adopted). Toxicity: Acute oral LD50 for rats 720 mg/kg (quoted, RTECS, 1985). Uses: Solvent for cellulose acetate, lacquers, vinyl resins, fats, oils, dyes, synthetic rubbers; chemical intermediate; propellant; gasoline additive.
