ABSTRACT
O CASRN: 76-22-2; DOT: 2717; DOT label: Flammable solid; molecular formula: C10H16O; FW: 152.24; RTECS: EX1225000; Merck Index: 12, 1779 Physical state, color, odor, and taste: Colorless to white, flammable granules, crystals or waxy semi-solid with a strong, penetrating, fragrant or aromatic odor. Odor threshold concentration is 0.27 ppm (quoted, Amoore and Hautala, 1983). Melting point (°C): 167.4-172.9 (Abrosimov et al., 2003) Boiling point (°C): Sublimes at 204 (Weast, 1986) Density (g/cm3): 0.990 at 25 °C (Weast, 1986) Diffusivity in water (x 10-5 cm2/sec): 0.78 at 25 °C using method of Hayduk and Laudie (1974) Flash point (°C): 65.6 (NIOSH, 1997) Lower explosive limit (%): 0.6 (NIOSH, 1997) Upper explosive limit (%): 3.5 (NIOSH, 1997) Entropy of fusion (cal/mol⋅K): 3.609 (Frandsen, 1931) 3.04 (Abrosimov, 2003) Heat of fusion (kcal/mol): 1.38 (Abrosimov, 2003) Henry’s law constant (x 10-5 atm⋅m3/mol): 3.00 at 20 °C (approximate - calculated from water solubility and vapor pressure)
8.76 (NIOSH, 1997) Soil organic carbon/water partition coefficient, log Koc: Unavailable because experimental methods for estimation of this parameter for cyclic ketones are lacking in the documented literature Octanol/water partition coefficient, log Kow: 2.74 (RP-HPLC, Griffin et al., 1999) Solubility in organics: At 25 °C (g/L): acetone (2,500), alcohol (1,000), benzene (2,500), chloroform (2,000), ether (1,000), glacial acetic acid (2,500), oil of turpentine (667). Also soluble in aniline, carbon disulfide, decalin, methylhexalin, nitrobenzene, petroleum ether, tetralin, higher alcohols, in fixed and volatile oils (Windholz et al., 1983). Solubility in water: ≈ 1.25 g/L at 25 °C (quoted, Windholz et al., 1983) 0.170 wt % at 20-25 °C (Fordyce and Meyer, 1940) Vapor pressure (mmHg): 0.2 at 20 °C (NIOSH, 1997) 0.65 at 25 °C (quoted, Jones, 1960) Exposure limits (mg/m3): NIOSH REL: TWA 2, IDLH 200; OSHA PEL: TWA 2, ceiling 4 ppm (adopted). Symptoms of exposure: Vapors may irritate eyes, mucous membranes and throat. Ingestion may cause headache, nausea, vomiting, and diarrhea (NIOSH, 1997; Patnaik, 1992). An irritation concentration of 10.62 mg/m3 in air was reported by Ruth (1986) for synthetic camphor. Toxicity: LC50 static bioassay values for fathead minnows after 1, 24, and 96 h are 145, 112, and 110 mg/L, respectively (Mattson et al., 1976). LD50 (intraperitoneal) for mice 3,000 mg/kg (quoted, RTECS, 1985). Source: Major component in pine oil (quoted, Verschueren, 1983). Also present in a variety of rosemary shoots (330-3,290 ppm) (Soriano-Cano et al., 1993), anise-scented basil leaves (1,785 ppm) (Brophy et al., 1993), Iberian savory leaves (2,660 ppm) (Arrebola et al., 1994), African blue basil shoots (7,000 ppm), Greek sage (160-5,040 ppm), Montane Mountain mint (3,395-3,880 ppm), yarrow leaves (45-1,780 ppm), and coriander (100-1,300 ppm) (Duke, 1992). Uses: Plasticizer for cellulose esters and ethers; manufacture of plastics, cymene, incense, celluloid; in lacquers, explosives, and embalming fluids; pyrotechnics; moth repellent; preservative in pharmaceuticals and cosmetics; odorant/flavorant in household, pharmaceutical, and industrial products; tooth powders.
