ABSTRACT

Introduction............................................................................................................291

Psammomys obesus

of the Jerusalem Colony ......................................................291 Diabetes Research in Other

Psammomys

Colonies .................................................................................................................292 Lipoprotein Synthesis in

Psammomys

..................................................................293 Beta Cell Lesion Following Prolonged Insulin Resistance with Hyperinsulinemia ..........................................................................................294 Selection of Defined Lines of

Psammomys

..........................................................296 Metabolic and Reproductive Efficiency ................................................................296 Age-Related Diabetogenicity ................................................................................298 Pregnancy in

Psammomys

.....................................................................................298 Inborn Insulin Resistance ......................................................................................298 Mechanism of Insulin Resistance and Attenuation of Receptor Tyrosine Kinase in

Psammomys

............................................................................299 Overexpression of PKC

ε

: A Negative Feedback of Insulin Signal Transduction ...............................................................................................300 PKC

ε

Overexpression: Relation to Muscle Lipid and Diacylglycerol (DAG) Content..............................................................................302 Effect of Exercise ..................................................................................................302 Evidence for a Major Gene Affecting Transition from Normoglycemia to Hyperglycemia in

Psammomys Obesus

............................................................302

Psammomys