ABSTRACT
Introduction..............................................................................................................62 Current Nomenclature for Mouse Mutations..........................................................63 Mutation Origins and Effect of Inbred Strain Background on Syndrome Development .....................................................................................64 Discovery of Molecular Nature of “
ob
” and “
db
” Mutations ................................65 Positional Cloning of “
ob
” and “
db
” Identifies Leptin and its Receptor .......................................................................................................66
