ABSTRACT
Histologic examination of exogenous ochronotic lesions reveals yellowish-brown or green, curled banana-shaped ochronotic fi bers [10]. In advanced stages, there is a degeneration of the ochronotic fi bers and the formation of a colloid milium. Stage III presents with infl ammatory mediators, including multinucleate giant cells, plasma cells, epithelioid cells, and histiocytes. Transepidermal elimination of pigment and pseudoepitheliomatous hyperplasia have also been described in severe cases [24,25].
