ABSTRACT
Ligand Peptide LLG-C4 .................................................................................93 7.5 Convergence of Research Lines-DDGW Peptide Inhibits proMMP-9
Binding to αMβ2 Integrin ................................................................................95 7.6 Catalytic and Noncatalytic Inhibition of Gelatinase-Mediated Cell
Migration and Invasion ...................................................................................95 7.7 Reduction of Workload by Recombinant Expression of Phage
Display Peptides..............................................................................................96 7.8 Conclusions .....................................................................................................97 References ................................................................................................................97
There are only 20 amino acids and a few modifications of them found in nature. Yet these few building blocks can generate a huge diversity of chains of different composition and length whereupon life is based. It can be estimated that only a minority of this diversity has evolved into proteins encoded by the genomes. There might be very specific rules that govern peptide-mediated interactions during protein folding and protein-protein interactions, but these may be so complex that we do not know them yet.
