Methods for Determining Bactericidal Activity and Antimicrobial Interactions: Synergy Testing, Time-Kill Curves, and Population Analysis

Appendix 12.1 — Worksheet Template for Broth Microdilution Checkerboard Panel ...............294 Appendix 12.2 — Example of a Broth Microdilution Checkerboard Panel ................................295 Appendix 12.3 — Worksheet Template for Broth Macrodilution Limited-Series

Checkerboard Format......................................................................................295 Appendix 12.4 — Example of Time-Kill Curve Showing Synergism and Antagonism .............296 Appendix 12.5 — Results of Checkerboard Represented as Isobolograms.................................297 References ......................................................................................................................................298