ABSTRACT

In this work we treat non-covalent interactions between biological and non-biological macromolecules, surfaces and particles. For the sake of simplicity of nomenclature we include hydrogen-bonding and other electron-donor-electron-acceptor interactions among the non-covalent interactions, even though some authors (see, e.g., Drago et al., 1971) classify these interactions as at least partly covalent. The non-covalent interactions under consideration are:

1. Electrodynamic, or Lifshitz-van der Waals (LW), interactions, 2. Polar, electron-donor-electron-acceptor, or Lewis acid-base (AB)

interactions, 3. Electrostatic (EL) interactions, and 4. Brownian movement (BR).