ABSTRACT

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Chiral molecules are ubiquitous in nature and have ever-increasing importance in the

pharmaceutical industry. This process started with Cushny’s observation that one enantiomer

of hyoscamine possessed greater pharmacological activity than the other. Thus, chirality of

drugs and pharmaceuticals has been in the focus of interest for several decades. The discovery

or design and the development of new drugs have been influenced to a great extent by a new

understanding of molecular recognition in many pharmacologically relevant events [1-5].