ABSTRACT

A pharmaceutical scientist will eventually face the task of formulating an oily or an oilsoluble m edicam ent in liquid formulation as a solid dosage form using the soft gela­ tin capsule, sometimes referred to as softgel or liquigel™. In the formulation of com ­ m on oral dosage forms, the formulator has access to excipients and processing technologies, thus enabling him to conduct a systematic formulation and processdevelopment research and produce an elegant and stable dosage form. On the other hand, due to its nature, the softgel technology has become specialized processing in which the formulator will rely on the others to produce the shell formulation and con­ ducts the shell-content compatibility studies. A suitable formulated m edicam ent is finally encapsulated as the content into a compatible soft gelatin shell.