ABSTRACT

I. Introduction .................................................................................................................... 565

II. Anatomy and Composition ............................................................................................ 566

III. Function .......................................................................................................................... 567

IV. Meniscal Cells ................................................................................................................ 569

V. Cell Sources for Tissue Engineering ............................................................................. 569

VI. Scaffolds ......................................................................................................................... 570

A. Synthetic Polymers ................................................................................................ 571

B. Biological Scaffolds ............................................................................................... 572

C. Hydrogel Scaffolds ................................................................................................. 575

D. Inert Nonresorbable Materials ............................................................................... 577

VII. Conclusions .................................................................................................................... 578

References ................................................................................................................................... 578

Once described as “functionless remnants of leg muscle origin,”

the menisci in the knee are now

regarded as important structures for knee stability, shock absorption, and load distribution.