ABSTRACT
This protein is essential for allowing platelets to adhere to collagen as well as to one another.
• Once platelets have undergone the process of adhesion, substances such as thrombin, thromboxane A
and ADP lead to further platelet
activation
. Activated platelets now release the contents of their
internal granules, which include substances such as ADP, fibrinogen, thrombin, thromboxane A
and von Willebrand’s factor, which induce the
aggregation
of additional platelets at the injury site.