ABSTRACT
Methods.................................................................310 20.3.1 Identification of Presented Peptides by Mass Spectral Analysis ..........................310
20.3.1.1 Basics of Mass Spectrometry................................................................311 20.3.1.2 Identification of Peptide Epitopes by Mass Spectrometry ...................311 20.3.1.3 Applications...........................................................................................312
20.3.2 Identification of Functional Epitope Determinants by Cell-Based Analysis........312 20.3.2.1 Tetramer Binding Analysis....................................................................312 20.3.2.2 ELISPOT Analysis ................................................................................313 20.3.2.3 Proliferation Responses.........................................................................314 20.3.2.4 I-mune
