ABSTRACT
See also PROTEIN, STORAGE PROTEINS, SOYBEAN PLANT, ALLERGIES (FOODBORNE), REDUCED-ALLERGEN SOYBEANS, GENE, GENETIC ENGINEERING, GENE SILENCING, RNA INTERFERENCE (RNAi), COSUPPRESSION, BIOTECHNOLOGY
p53 Gene Discovered in 1978 by David Lane, it is a tumor suppressor gene that controls passage of a given cell from the “GI” phase to the “s” (i.e., DNA synthesis) phase. The p53 protein that is coded for by the p53 gene is a transcription factor (i.e., it “reads” DNA to determine if it is damaged and then acts to control cell division, whereas the p53 gene codes for more production of additional p53 protein). The p53 gene was discovered in 1993 by Arnold J. Levine and colleagues to be responsible for approximately 50% of all human cancer tumors (when the gene is damaged or mutated).
