ABSTRACT
See also DNA VACCINES, “NAKED” GENE, EDIBLE VACCINES, PEYER’S PATCHES, ANTIGEN, CELLULAR IM M UNE RESPONSE, HUMORAL IMMUNITY, CARRIER PROTEIN, CELL SURFACE ENGINEERING
Vaccinia A nonpathogenic virus that is believed to be a (modified) form of the virus that causes cowpox. Vaccinia readily accepts genes (inserted into its genome via genetic engineering) from pathogenic viruses so it can be used to make vaccines that do not possess the risk inherent in attenuated-virus vaccines (i.e., that the attenuated virus “revives” and causes disease). Such genetically engineered Vaccinia codes for (presents) the proteins of the pathogenic virus on its surface, which activates the immune system (e.g., of vaccinated animal) to produce antibodies against that pathogenic virus.
