ABSTRACT

Effects of various gold compounds on human health are documented in this chapter, except effects associated with the use of gold drugs to treat rheumatoid arthritis, which are covered in detail in Chapter 9. This chapter specifically reviews (1) the history of gold drugs in medicine; (2) adverse reactions to gold treatments, including possible lethal, carcinogenic, and teratogenic effects; (3) case histories documenting hypersensitivity, Goldschlager syndrome, and other effects; and (4) dental aspects of gold, including allergic and sensitization reactions documented by selected case histories.