ABSTRACT
Magnetic resonance imaging (MRI), introduced in late 1970s, flourished in clinical applications. Knowledge accumulation from many years of basic nuclear magnetic resonance research realized the hope of obtaining information about the biochemistry, perfusion, and metabolism that can be coupled to energy consumption and
functional
activity in the examined tissues (fMRI). First appearing in the early 1990s,
fMRI gained almost immediate popularity in both basic research in the life sciences and in the clinical diagnosis of various diseases.
