ABSTRACT

Ichnovirus Geno~ne ................................................................................................. , 2 0 7 11.4.3 Genes Encoding olydnavirus Structural Proteins.. ............................................. 208

1 1.5 Relationships etween Genome Organization and Viral Gene Function ......................... 2 0 9 11.6 Summary ............................................................................................................................... 212 Acknowledgnients .......................................................................................................................... 213

There is considerable evidence that genes have ~ ~ i o v e d across species boui~dai-ies over evoluiionary time with several genetic elements such as plasnids, vinses. and transposable elements implicated in gene transfer (e.g.. Andersson and Kurland, 1998a). The impact of these niobik DNA elements is evident both within individual genomes and at the population and species levels. Much of transgenic research has been directed toward undersian ing these naturally occurring mobile elements to expioit preexisting mechanisms for gene delivery and integration. The resuits of this approach to transgenesis have been spectacularly successfd and continue to have great potential for application in the future.