ABSTRACT

Image 21-2 Carbon monoxide toxicity If the victim survives for days or weeks, he or she will develop areas of necrosis that are characteristically located in the globus pallidus. Necrosis may also be seen in the substantia nigra and hippocampi. There may also be widespread white matter damage (Grinker’s myelinopathy). This example is from a 4-yearold child who survived for 13 hours after sustaining carbon monoxide poisoning. Note the necrotic basal ganglia.