ABSTRACT
In an interesting case of synergy, Jin et al. (1999) show that aloesin and arbutin inhibit tyrosinase synergistically, acting via different mechanism.
And death from stomach inflammations have resulted from frequent and large doses of the oil. The highest average maximum use level is ca. 0.04% in candy. Not listed under FDA §172.510, 182.10, or 182.20. Wintergreen has lectinic, including mitogenic properties. Salicylism usually marked by tinnitus, nausea, and vomiting and may result from excessive dosage of salicylic acid and/or its salts.
