ABSTRACT
In rural Sudan, powdered seeds are used to purify drinking water by coagulation. In trials, the powder was toxic to guppies (
Poecilia reticulata
), protozoa (
Tetrahymena pyriformis
), and bacteria (
Escherichia coli
), and it inhibited acetylcholinesterase. It might serve as a fruit-and vegetable-preservative. In low concentrations, it protects mice against
staphylococcus
infections. Juice from the leaves and stem bark inhibits
Staphyloccoccus aureus
but not
Escherichia coli
. One study showed bark extracts active against
Bacillus subtilis, Dip. pneumoniae, Escherichia coli, Micrococcus pyogenes, Salmonella typhosa, Shigella dysenteri, Streptococcus pyogenes,
and
Vibrio comma
. Bark extract fungicidal to
Candida albicans, Helminthosporium sativum, Microsporum gypseum
, and
Trichiphyton mentagrophytes
. The 50% ethanolic extract of root bark (devoid of antibacterial activity) was antiviral to the vaccinia virus but not Ranikhet disease virus, but it did inhibit its replication. Ether leaf extracts were bacteriostatic to
Staphylococcus aureus
and
S. typhosa
. Alcohol extracts may contain an adrenergic neurone blocking agent (MPI).
