ABSTRACT
Neurotoxicology is the subdiscipline of toxicology that focuses on the adverse effects of chemicals on the nervous system. Broadly defined, neurotoxicity is any adverse effect on the structure or function of the central and/or peripheral nervous system related to exposure to a chemical substance.1-3 The foundation for understanding the toxic effects of chemicals on the nervous system, and therefore the science of neurotoxicology, is strongly influenced by contributions from the neurosciences. A thorough study of neurotoxicity includes several levels of analysis of chemical interactions within the nervous system: from the chemical or molecular level, progressing to the cellular and organ level, and ultimately to the whole animal or organismic level. Therefore, the science of neurotoxicology is truly multidisciplinary, founded on basic scientific principals drawn from toxicology, neurochemistry, neuropathology, electrophysiology, and psychology.
