ABSTRACT
Carcinogenicity Used for Interpretative Conclusions Regarding Chronic Rodent Carcinogenicity Study Results
Table 16.13 Top Ten Organs/Systems Developing Tumors in Carcinogenesis Studies — Mice
Table 16.14 Top Ten Organs/Systems Developing Tumors in Carcinogenesis Studies — Rats
Table 16.15 Frequency of Carcinogenic Response to Chemicals by Organ/System — Rats and Mice
Table 16.16 Animal Neoplastic Lesions of Questionable Significance to Humans
Section 5. Tumor Pathology Table 16.17 Capacity of Tissues to Undergo Hyperplasia
Table 16.20 Selected Taxonomy of Neoplasia
Section 6. Glossary of Terms Related to Carcinogens References
Cancer ranks as the toxic effect of most concern to the public. Because of this, considerable effort and financial resources are spent annually to identify potential human carcinogens. The purpose of this chapter is to supply basic information pertaining to carcinogenesis in rodents which is essential for understanding and interpreting the results of chronic rodent carcinogenicity studies.
