ABSTRACT

A. Food and Water Requirements Table 1.5 Approximate Daily Food and Water Requirements for Various

Species B. Fasting

Section 13. Anesthesia and Analgesia A. General Considerations B. Controlled Substances C. Relevant Definitions D. General Principles Regarding Anesthesia, Analgesia, and

Tranquilization E. Stages of Anesthesia F. Methods of Administration G. Commonly Used Anesthetic, Analgesic, and Tranquilizing Agents

Table 1.6 Typical Routes and Dosages of Several Sedative, Analgesic, and Anesthetic Agents

H. Species Peculiarities and Contraindications Section 14. Euthanasia

A. Modes of Action B. Euthanasia Methods and Agents

Table 1.7 Acceptable and “Conditionally Acceptable” Methods for Euthanasia of Several Common Laboratory Species

Table 1.8 Summary of the Characteristics of Several Euthanasia Methods

Section 15. Sources of Laboratory Animals Table 1.9 Names, Addresses, and Phone Numbers of Several Animal

Suppliers Section 16. Species Data

A. Mouse (Mus musculus) Table 1.10 Common Strains of Laboratory Mice Table 1.11 Minimum Cage Space Requirements for Mice Table 1.12 Physical and Physiological Parameters of Mice Table 1.13 Identification, Bleeding, Anesthesia, and Euthanasia Methods

for Laboratory Mice Table 1.14 Various Diseases and Adverse Health Conditions of Laboratory

Mice B. Rat (Ratus norvegicus)

Table 1.15 Common Strains of Laboratory Rats Table 1.16 Minimum Cage Space Requirements for Rats Table 1.17 Physical and Physiological Parameters of Rats Table 1.18 Identification, Bleeding, Anesthesia, and Euthanasia Methods

for Laboratory Rats Table 1.19 Various Diseases and Adverse Health Conditions of Laboratory

Rats C. Guinea Pig (Cavia porcellus)

Table 1.20 Minimum Cage Space Requirements for Guinea Pigs Table 1.21 Physical and Physiological Parameters of Guinea Pigs

Table 1.23 Various Diseases and Adverse Health Conditions of Guinea Pigs

D. Rabbit (Oryctolagus cuniculus) Table 1.24 Minimum Cage Space Requirements for Rabbits Table 1.25 Physical and Physiological Parameters of Rabbits Table 1.26 Identification, Bleeding, Anesthesia, and Euthanasia Methods

for Laboratory Rabbits Table 1.27 Various Diseases and Adverse Health Conditions of Rabbits

E. Dog (Canis familaris) Table 1.28 Minimum Cage Space Requirements for Dogs Table 1.29 Physical and Physiological Parameters of Dogs Table 1.30 Identification, Bleeding, Anesthesia, and Euthanasia Methods

for Laboratory Dogs Table 1.31 Various Diseases and Adverse Health Conditions of Dogs

References Additional Related Information

Table 1.32 Guiding Principles in the Use of Animals in Toxicology Table 1.33 General Information Sources for the Care and Use of Research

Animals Table 1.34 Commonly Used Anesthetics Table 1.35 Advantages and Disadvatanges of Anesthetic Agents and

Adjuncts

The use of live animals continues to be an important and necessary component of research activities worldwide. To ensure the ethical and humane treatment of animals, scientists must possess a sound understanding of appropriate animal husbandry practices and must be knowledgeable of those variables which may impact and potentially confound experimental procedures and results.