ABSTRACT
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Mapping biological processes involved in development and pathology was largely conÞned to postmortem histological examinations or
in vitro
experimentation of cellular events. The ability to probe biological processes and anatomies of living systems was, to say the least, limited. The recent development of imaging technologies such as magnetic resonance imaging (MRI) that can scrutinize soft living tissue (such as brain and muscle) has allowed the investigation of anatomical structures and biological processes
in vivo
. Examination of the temporal progression of development and pathology will undoubtedly enhance our understanding of how structural
changes relate to functional development and/or impairment. For example, in humans, the use of MRI and related imaging techniques has greatly enhanced our ability to diagnose a variety of pathologies.