ABSTRACT
Receptor Activity................................................................................. 63 4.3.3 Molecular Mechanisms Mediating Facilitation of NMDA
Receptor Function by Ethanol ............................................................. 63 4.3.4 Brain Region-Specific Actions of Ethanol ..........................................64 4.3.5 Chronic Ethanol and Synaptic Compartmentalization of NMDA
Receptor Subunits ................................................................................65 4.3.6 Chronic Ethanol Exposure and Withdrawal Alters NMDA
Receptor Function ...............................................................................65 4.4 Physiological Implications of Modulation of NMDA Receptor Function
by Ethanol .......................................................................................................66 4.4.1 Acute Inhibition ...................................................................................66 4.4.2 Acute Tolerance, Rebound Potentiation, and LTF .............................. 67 4.4.3 Chronic Ethanol Exposure and Withdrawal ....................................... 67
4.5 NMDA Receptors and Behaviors Associated with Ethanol Exposure ...........68 4.5.1 Ethanol Intoxication ............................................................................68 4.5.2 Sensitization ........................................................................................68 4.5.3 Reward .................................................................................................68 4.5.4 Relapse ................................................................................................69 4.5.5 Ethanol Withdrawal Syndrome ...........................................................69
4.6 Modulators of NMDA Receptor Function and Treatment of Alcohol Abuse and Dependence ...................................................................................69
Acknowledgment ..................................................................................................... 70 References ................................................................................................................ 70
