The purpose of the workshop was to allow for a focused discussion regarding the fate and effects of metals in the environment (the focus was on inorganic substances; however, where appropriate, organometallic substances were also considered) and incorporating important advances in the state of knowledge that had occurred in the intervening 7 years. Specifically, this workshop allowed for a forum for further discussions among scientists, environmental regulators, and environmental managers, on the utility of persistence, bioaccumulation, and toxicity (PBT) for hazard identification and classification procedures for metals and inorganic metal substances.