ABSTRACT

Metaphase Chromosomes ........................................................................113 9.7 Dynamic Changes in the Structure of the Chromosome during

Cell Division .............................................................................................115 9.8 Conclusion ................................................................................................116 Acknowledgments ..............................................................................................116 References ..........................................................................................................116

Chromosomes are the intracellular structures that appear as the devices for segregating genetic material during cell division. Biochemical studies have revealed that chromosomes are composed of DNA, histones and nonhistone proteins (see Chapter 13). The structure of the chromosomes has been most often studied at