ABSTRACT
The interactions between proteins and low molecular weight surfactants have broad relevance in many biotechnological disciplines. These interactions play a decisive role in applications such as drug delivery, cosmetics, and solubilizing processes used for the extraction, isolation and puri cation of biological macromolecules to name but a few. Moreover, since the fundamental principles underlying the formation of protein-micellar complexes are common to other assemblies such as reverse micelles, bilayers, liposomes, and biological membranes [1,2], an understanding of these interactions can be used to our advantage in the selection of the surfactant [3,4]. Therefore, the study of the interactions responsible for the binding of surfactants to proteins has been the subject of extensive research for many years using a number of different experimental techniques [4-7].
