ABSTRACT
Phosphorylation of protein was discovered in the era of allosteric regulation. Regulation of enzyme activity could be explained by the concentration of substrates, the presence of cofactors, and the concentration of the end product (allosteric effectors). One of the pathways thus analyzed
8.1 Phosphorylation as a Switch in Cellular Functioning...........................................................225 8.2 Growth Factors, Interleukins, Interferons, and Cytokines ...................................................226 8.3 Color Illustrations ................................................................................................................. 227 8.4 Receptors That Contain Tyrosine Protein Kinases............................................................... 227
8.4.1 Dimerization and Transphosphorylation of Receptors Cause Their Activation ....... 227 8.4.2 Src Homology and PTB Domains and the Formation of Receptor Signaling
Complexes .................................................................................................................228 8.4.3 Branching of the Signaling Pathway ........................................................................230
