ABSTRACT
Pharmaceutical profiling assays provide early assessments of drug-like properties such as solubility, permeability, metabolism, stability, and drug-drug interactions. This information can be used to alert project teams to potential property issues, predict and diagnose in vitro and in vivo assay results, guide structure-property relationships, provide insight into structure modification, and help drug discovery teams make informed decisions. Successful drugs can be developed when biological activities of interest and pharmaceutical properties are optimized in parallel.
