ABSTRACT

Asthma is emerging as an increasingly prevalent disease in the developed world with incidences on the rise in developed countries. It is a complex inammatory disease characterized by airways obstruction, bronchial hyperresponsiveness, accompanied by eosinophilic and neutrophilic inammation. Upon activation, local immune and

Abstract .................................................................................................................. 149 Asthma as a Growing Public Health Concern ....................................................... 150 Current Asthma Treatment Options ....................................................................... 150 Biology of Tumor Necrosis Factor-α .............................................................................152