ABSTRACT

As the manufacturing technologies advance and experimental protocols optimize, the comparability between microarray experiments improves. However, reproducibility also depends on details (e.g., parameters and normalization) in the experiment and analysis. Therefore, it is helpful, and has become mandatory, that raw microarray data – DNA methylation, histone modifications or gene expression – along with information on the assay and analysis are made available in public data repositories for free assessment by third parties. We describe the minimum prerequisite information about a microarray experiment for publication to most scientific journals and the most popular public warehouses for data deposition, after an introduction to the international organization that promotes DNA methylation and epigenetics.