ABSTRACT

Osteoporosis, literally “porous bone,” is defined as a reduction in the mass and quality of bone and/ or the presence of a fragility fracture. Osteoporosis is common, preventable, serious, diagnosable, and treatable. Osteoporosis is a clinically silent systemic skeletal disease characterized by compromised bone strength predisposing to an increased risk of fracture. It can occur as a primary disease or secondary to underlying chronic disease or use of certain medications (Table 32.1). Osteoporosis can be prevented or ameliorated by lifestyle interventions. This chapter imparts a science-based understanding of the etiology and pathophysiology, which enables an interested clinician to diagnose osteoporosis and apply nutritional interventions.