ABSTRACT

The term bioconjugate is well accepted in the scientic literature but undened in, for example, The Oxford Dictionary of the English Language; yet, it is beyond de- nition as a neologism. Meares1 dened a bioconjugate as the joining of two molecular functions by either chemical or biological means. Bioconjugates are most frequently the combination of a well-known protein such as albumin, immunoglobulin, or immunoglobulin fragment with a nonprotein moiety such as cytotoxic agents.2-4 The term bioconjugate has also been dened as a coupled protein reagent.5 Having said this, a compound is a bioconjugate in the eye of the viewer.