ABSTRACT

Mass spectrometers do one thing-they measure mass. In proteomics, the mass gives information on the protein identity, its chemical modifications, and its structure. Every mass spectrometer has three main components: a source, an analyzer, and a

5.1 Introduction .................................................................................................... 71 5.2 MS Source Design .......................................................................................... 72 5.3 Liquid Chromatography-Mass Spectrometry Considerations ....................... 76 5.4 Mass Analyzers...............................................................................................80