ABSTRACT

The heterogeneous superfamily of amine oxidases (AOs) includes enzymes found in all living systems, ranging from prokaryotes to eukaryotes. These enzymes are involved in cellular and extracellular metabolism of amines (monoamines, diamines, and polyamines) whose oxidation may generate other biologically active substances like aldehydes, ammonia, and hydrogen peroxide. The classication of copper amine oxidases (CAOs) takes into account their origins and substrate specicities and includes mammalian, microbial, and plant amine oxidases.