ABSTRACT
The Greeks were probably the rst to recognize the difference between an acute and chronic wound (i.e., fresh versus non-healing), and Galen of Pergamum, who served the gladiators performing in Rome (circa 120−201 a.d.) also recognized the importance of wound site moisture for successful closure. However, it was not until the 16th century that Ambroise Paré, the French military barber/surgeon, conducted what might be considered the rst controlled clinical trial regarding wound healing.1
Introduction ............................................................................................................ 345 Pressure Ulcers as an Example of Chronic Wounds .........................................346
Colonization, Infections, and Wound Healing ....................................................... 347 The Chronic Wound: What to Do? .........................................................................348
