ABSTRACT
Chromatography (RPLC) Retention Mechanism ........................................... 11 1.3.1 The Simulation Approach ................................................................... 12 1.3.2 The Driving Forces for Reversed-Phase Liquid Chromatography
(RPLC): Solvophobic or Lipophilic? .................................................. 12 1.3.3 Do Chains Lie Extended Away or Cover the Surface? ....................... 15 1.3.4 Where Is the Solvent? .........................................................................20 1.3.5 Partition or Adsorption?...................................................................... 21 1.3.6 Effects of Embedded Polar Groups ....................................................25 1.3.7 Determination of the Phase Volumes .................................................26 1.3.8 Pressure and Pore Curvature Effects ..................................................27 1.3.9 General Observations for the Bonded-Phase-Solvent-Solute
Environment .......................................................................................27
