ABSTRACT

The invention of the open-tubular capillary (OTC) column [1] can certainly be considered one of the fundamental events in the history of gas chromatography (GC), since its introduction in 1952 [2]. Through Golay’s intuition, the unsuspected high complexity of many real-world samples has been revealed in the last ve decades. Today, single-column GC is the most commonly applied method for the analysis of volatiles and semi-volatiles.