ABSTRACT
The liver is the largest organ in the body and is involved in numerous metabolic pathways, such as the regulation of carbohydrate, lipids, and proteins. The specic functions of the liver also include steroid hormone synthesis, drug detoxication, and bilirubin conjugation (Figure 1.1). More recently, investigations have been focusing on how components of the diet, in particular fatty acids, may regulate lipogenic pathways. As a consequence, current and future research is now heavily targeting transcriptional factors that are possibly involved in these pathways. This may lead to newer drug interventions for disorders such as obesity and fatty liver disease (alcoholic and nonalcoholic).
