ABSTRACT
Excessive release of reactive oxygen species (ROS) leads to oxidative stress which has been implicated in the pathogenesis of numerous chronic diseases and health conditions. Although ROS can be beneficial in immune response by killing pathogens and removing injured tissues, they act as a major tissue destructive force when overproduced as in various inflammations. Inflammation is an important component of many chronic diseases and age-related disorders. Metabolic syndrome, for example, has been associated with chronic inflammation, especially in adipose tissues. Therefore, effective control of inflammation is important in the prevention and treatment of such chronic diseases. Antioxidant strategies have been proposed for suppressing inflammation by scavenging the pro-inflammatory ROS, and hence reducing the risk of many inflammation-mediated diseases.
