ABSTRACT

Diet-induced obesity and the subsequent development of features of the metabolic syndrome have become major worldwide health problems. According to the National Center for Health Statistics more than 34% of the U.S. population is obese and almost 70% of adults in the U.S. are overweight. Obesity has and continues to threaten and overload health care infrastructures due to association with various chronic diseases including increased risk of certain cancers, type II diabetes mellitus (T2DM) and cardiovascular complications and diseases [1]. Reduced life expectancy and degradation of elderly life quality due to obesity and its related diseases appear imminent. Obesity is associated with low-grade inflammation in adipose tissues resulting from increased production of pro-inflammatory cytokines that can subsequently contribute to the development of insulin resistance [2-4].