ABSTRACT
Mass Spectrometric Detection ......................................................................207 6.2.1 In Vitro and In Vivo Reactive Metabolite Pro ling ..........................207 6.2.2 Glutathione Adducts .........................................................................207 6.2.3 Cyanide Adducts ............................................................................... 215 6.2.4 Other Peptides ................................................................................... 216 6.2.5 Cobalamine ....................................................................................... 217 6.2.6 Electrochemical System for Metabolite Generation ......................... 218
6.3 Covalent Binding to Proteins ........................................................................220 6.4 Conclusions ...................................................................................................224 Acknowledgment ...................................................................................................225 References ..............................................................................................................225
