ABSTRACT

The design and development of clean organic transformations remains a current and challenging goal for the synthetic community. To this end, minimization of decomposition and secondary reactions while simplifying the purication of target compounds has been the subject of intense research. Microwave-assisted reactions have become very popular in the synthetic community due to the drastically reduced reaction times and minimization of secondary reactions.1 The operational simplicity of microwave apparatus may be one of its greatest attributes as researchers can run dozens of screening reactions in a single day. Another advantage of microwave-assisted chemistry is the precise control over several reaction parameters such as microwave power, time, and temperature. Thus, nding the optimal conditions for a specic reaction has almost been trivialized.