Artificial Feeding of an n-3 Essential Fatty Acid–Deficient Diet Leads to a Loss of Brain Function in the First Generation

One limitation of the work on animal n-3 deficiency is that the dietary conditions do not model well the human situation. It would thus be valuable if neural DHA levels could be significantly reduced so that changes in function could be evaluated in pups born to mothers who had not been deprived of dietary n-3 fatty acids. This would then be a “first generation” model of n-3 deficiency.